The Ultimate Guide to Polynucleotide Treatments

If you’re looking for a natural and effective way to rejuvenate your skin, polynucleotide treatments might be the perfect solution. This innovative treatment is taking the aesthetics world by storm, offering impressive skin-repairing and anti-ageing benefits without the need for synthetic fillers or toxins. Whether you’re dealing with fine lines, dehydration, or skin damage, polynucleotides provide deep cellular repair to restore your skin’s vitality.

At our clinic in Southampton, we specialise in advanced injectable treatments, including polynucleotides, to help you achieve a refreshed and youthful complexion. In this guide, we’ll explore everything you need to know about polynucleotide treatments—how they work, what to expect, and how often you need them to maintain your results.

Polynucleotides are an innovative skin-rejuvenating treatment designed to repair and regenerate skin at a cellular level. Derived from purified DNA fragments, polynucleotides act as biostimulators, encouraging natural healing processes in the skin and improving overall skin quality. They are gaining popularity in aesthetic medicine due to their ability to hydrate, smooth, and restore the skin without the use of synthetic fillers or toxins.

Polynucleotides work by stimulating fibroblasts—the cells responsible for collagen and elastin production—helping to repair damaged tissue and improve skin elasticity. They also enhance hydration by attracting and retaining moisture in the skin. Additionally, polynucleotides possess powerful anti-inflammatory properties, making them highly effective for sensitive, damaged, or ageing skin.

Polynucleotide treatments can be administered in multiple areas of the face and body to improve skin quality and promote regeneration.

The most popular areas include the under-eye region to reduce dark circles and fine lines, the cheeks to enhance skin firmness and hydration, and the forehead to smooth out fine lines. Polynucleotides are also effective in treating the neck and décolletage, where the skin often shows signs of ageing and sun damage.

Additionally, they can be used on the hands to restore lost volume and improve texture, as well as on areas with acne scars or stretch marks to aid in tissue repair and regeneration. The versatility of polynucleotides makes them an excellent choice for a range of aesthetic concerns.

Polynucleotide treatments are incredibly versatile and can address a range of skin concerns, including:

• Fine lines and wrinkles
• Skin laxity and loss of firmness
• Dehydration and dullness
• Acne scarring and skin texture irregularities
• Under-eye hollows and dark circles
• Sun damage and pigmentation
• Rosacea and inflammatory skin conditions

The polynucleotide solution is derived from natural biopolymers, which are highly compatible with human skin. These DNA chains undergo an extensive purification process to ensure they are safe and effective for aesthetic use. The treatment is completely biocompatible and free from synthetic chemicals, making it suitable for sensitive skin types.

Yes, polynucleotide treatments are FDA-Approved and are extremely safe when administered by trained professionals. As they are derived from natural DNA sources, the risk of allergic reactions is minimal. The treatment is also free from harmful additives, and side effects are usually mild, including temporary redness, swelling, or minor bruising at the injection site.

Polynucleotide treatments involve a series of small injections into targeted areas of the skin, the needle used is extremely fine and the procedure is relatively quick and well-tolerated. Some patients may experience mild discomfort during the injections, but a numbing cream can be applied beforehand to enhance comfort. After the treatment, you may feel slight tenderness or swelling, which typically resolves within a few hours to a couple of days.

A polynucleotide treatment session usually takes between 30 to 45 minutes, depending on the area being treated. The process includes consultation, skin preparation, and the injection procedure itself.

Results from polynucleotide treatments develop gradually as the skin regenerates. Most patients notice improved hydration and radiance within a few weeks, with full effects becoming visible after 6 to 8 weeks. The results typically last between 6 to 12 months, depending on skin type, lifestyle, and maintenance treatments.

After a polynucleotide treatment, you can expect:

• Increased skin hydration and elasticity
• Smoother and firmer skin texture
• Reduced fine lines and wrinkles
• Brighter and more even skin tone
• Improved healing and repair of damaged skin

For optimal results, an initial course of 3 to 4 treatments, spaced 2 to 4 weeks apart, is typically recommended. To maintain the benefits, a top-up session every 6 to 12 months is advised, depending on individual skin needs.

To ensure the best results and minimise the risk of bruising, follow these pre-treatment guidelines:

• Avoid alcohol and blood-thinning medications (e.g., aspirin, ibuprofen) for at least 48 hours before your appointment.
• Stay well-hydrated to support skin healing.
• Avoid excessive sun exposure and tanning beds.
• Ensure your skin is clean and makeup-free on the day of treatment.

• Avoid touching the treated area for at least 6 hours post-procedure.
• Refrain from strenuous exercise, saunas, or hot showers for 24 hours.
• Apply a soothing moisturiser and avoid harsh skincare products for a few days.
• Protect your skin with a high-SPF sunscreen to maintain results.

Polynucleotide treatments are an excellent choice for anyone looking to enhance their skin’s natural repair process while achieving long-term rejuvenation. Unlike temporary solutions, this treatment works on a deep cellular level to restore hydration, stimulate collagen production, and improve skin texture over time. Address multiple skin concerns at once with minimal downtime and an excellent safety profile.

Whether you are dealing with fine lines, loss of firmness, or post-inflammatory pigmentation, this treatment helps restore balance and vitality to the skin. The results are natural-looking and long-lasting, making it an appealing alternative to traditional dermal fillers or more invasive procedures.

Polynucleotide treatments offer a revolutionary approach to skin rejuvenation, delivering hydration, elasticity, and visible improvements in skin quality. With regular treatments, you can maintain a youthful, refreshed look while supporting your skin’s long-term health.

If you’re considering polynucleotide treatment in Southampton, we’re here to help. Our team of injectable specialists provides tailored treatments to suit your skin’s unique needs. Contact us to book a consultation and start your journey to healthier, rejuvenated skin!